Fig. 5.

Frequency of Igβ/IgH translocations in mutant B cells. (A) Graphs represent number of translocations per 10⁶ cells from wild-type, AID^−/−, ATM^−/−, p53^−/−, and p19^−/− B cells. c-myc/IgH (left) and Igβ/IgH (right) translocation frequency obtained from the same DNA samples. (B) Igβ/IgH translocations in wild-type B cells supplemented with BAFF or PKCδ^−/− B cells. Graph represents the comparison of translocation frequencies from three independent samples in which a total of 10 million cells were assayed.