Table 3.
Coefficients of the Correlations of Hemodynamic, Ventricular Function, and Ventilatory Gas Exchange Parameters at Rest and at Peak Exercise With VE/VCO2 Slope Measured Throughout Exercise and the Change in VE/VCO2 Slope Between 0 and 12 Weeks
| VE/VCO2 Slope Correlation With Parameters |
Change in VE/VCO2 Slope Correlation With Parameters |
|||
|---|---|---|---|---|
| Parameter | At Rest | At Peak Exercise | At Rest | At Peak Exercise |
| Hemodynamic | ||||
| Cardiac index | −0.26 (0.05) | −0.32 (0.01) | −0.29 (0.12) | −0.43 (0.02) |
| Mean right atrial pressure | −0.05 (0.72) | −0.07 (0.59) | 0.12 (0.51) | 0.28 (0.14) |
| Mean pulmonary arterial pressure | 0.52 (<0.001) | 0.30 (0.02) | 0.54 (0.002) | 0.47 (0.01) |
| Mean PCW pressure | 0.43 (<0.001) | −0.07 (0.61) | 0.51 (0.004) | 0.06 (0.77) |
| Pulmonary vascular resistance | 0.39 (0.002) | 0.60 (<0.001) | 0.31 (0.10) | 0.69 (<0.001) |
| Systemic vascular resistance | 0.24 (0.06) | 0.30 (0.02) | 0.24 (0.21) | 0.30 (0.11) |
| Ventricular function | ||||
| RVEF | −0.20 (0.12) | −0.29 (0.03) | −0.58 (<0.001) | −0.40 (0.03) |
| LVEF | −0.07 (0.63) | −0.15 (0.28) | −0.21 (0.28) | −0.08 (0.66) |
| Ventilatory gas exchange | ||||
| PaCO2 | −0.56 (<0.001) | −0.69 (<0.001) | −0.24 (0.23) | −0.46 (0.01) |
| VD/VT | 0.26 (0.048) | 0.42 (0.001) | 0.04 (0.84) | −0.57 (0.002) |
| PaO2 | 0.23 (0.08) | −0.01 (0.93) | −0.06 (0.76) | 0.06 (0.76) |
| pH | 0.26 (0.05) | 0.30 (0.02) | −0.19 (0.33) | −0.17 (0.38) |
| C(a-v)O2 | 0.20 (0.13) | 0.01 (0.96) | 0.30 (0.11) | 0.03 (0.86) |
Data are presented as R (P value).
PCW indicates pulmonary capillary wedge, VD/VT, fractional dead space volume relative to tidal volume.