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. 2010 Jan 14;5(1):e8710. doi: 10.1371/journal.pone.0008710

Figure 2. TRα1/TRβ deficiency results in delayed hepatocyte proliferation after PH.

Figure 2

(A) Effect of TRα1/TRβ deficiency on survival rates after PH (n = 19–32); animal death occurred in the first 24h post-PH. (B) Percentage of Ki67-positive cells in liver sections. (C) Hepatocyte ploidy distribution determined in preparations of liver disaggregated cells in a Medimachine. (D) Time-course of PCNA, cyclins E and D1, C/EBPα and C/EBPβ protein levels determined in liver extracts after PH. Results show means ± SD of 6 animals per condition (B,C) or a representative blot of three (D). *P<0.05, **P<0.01 vs. WT condition.