Mean (±SE) association of plasma pyridoxal 5′-phosphate (PLP) concentration and chronic disease status. P values for mean differences between groups with and without a condition were adjusted for age, sex, smoking status, alcohol intake, physical activity, hormone use among women, dietary vitamin B-6, and folate, protein, and total energy intake in a general linear model. Black bars represent the percentage of vitamin B-6 inadequacy (PLP < 20 nmol/L). MetS, metabolic syndrome.