TABLE 3.
Rate of appearance of phenylalanine (in μmol · kg−1 · h−1) in pregnancy1
| Nonpregnant | First trimester | Second trimester | Third trimester | P2 | |
| Fasted | 42.1 ± 10.2 (8)3 | 31.9 ± 4.2 (10) | 40.9 ± 6.1 (5)3 | 43.5 ± 12.1 (10)3 | 0.019 |
| Fed | 56.5 ± 11.5 (8) | 45.0 ± 7.8 (10) | 56.6 ± 17.0 (5) | 51.1 ± 9.1 (5) | NS |
| Δ4 | 14.41 ± 4.58 (8) | 13.15 ± 5.75 (10) | 15.65 ± 11.26 (5) | 12.59 ± 2.89 (5) | NS |
1
All values are means ± SDs; n in parentheses.
2
Obtained by using Kruskal-Wallis one-factor ANOVA.
3
P < 0.05 compared with first trimester subjects (Mann-Whitney U test).
4
Fed minus fasted states.