Table 2.
Strain | Relative reversion rate
|
Suppression by mismatch repair msh2 | Relative reversion rate msh6 | Suppression by mismatch repair msh6 | |
---|---|---|---|---|---|
Wild-type | msh2 | ||||
YMH53 (A/A;T/T) | 1 | 1 | 1 | 1 | 1 |
YMH56 (T/C;A/G) | 1 | 2 | 2 | 13 | 13 |
YMH57 (A/C;T/G) | 1 | 3,100 | 3,100 | 3,300 | 3,300 |
YMH55 (C/C;G/G) | 11 | 12 | 1.1 | 12 | 1.1 |
YMH52 (C/A;G/T) | 24 | 17,000 | 710 | 15,000 | 630 |
YMH54 (G/A;C/T) | 24 | 56,000 | 2,300 | 63,000 | 2,600 |
Each parental reversion rate is compared to the lowest measurable rate of 1 × 10−10. Relative reversion rates are compared to the wild type. Note that the reversion rates shown for YHM53 are too low to be measured accurately and may be lower than indicated in the table.