Table 3.
Strain | Reversion rate, ×10−6
|
Anaerobic suppression | Mutation | |
---|---|---|---|---|
Aerobic | Anaerobic | |||
YMH57/msh2 | 0.31 | 0.025 | 12 | T → C |
YMH57/msh6 | 0.33 | 0.0099 | 33 | |
YMH52/msh2 | 1.7 | 0.038 | 45 | C → T |
YMH52/msh6 | 1.5 | 0.051 | 29 | |
YMH54/msh2 | 5.6 | 0.12 | 47 | G → T |
YMH54/msh6 | 6.3 | 0.10 | 63 |
Anaerobic suppression is the ratio of aerobic to anaerobic reversion rates. The mutation shown is the one most likely to occur due to oxidative damage (e.g., G → T rather than C → A).