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. 2010 Jan-Feb;3(1-2):45–56. doi: 10.1242/dmm.003749

Fig. 3.

Fig. 3.

p53I166T/I166T survival curves. (A) Using Kaplan-Meier analysis, p53I166T/I166T adult fish (n=144) had a significantly increased tumor incidence (P<0.0001) compared with p53+/+ fish (n=60). The first tumor was identified at 269 days (8.8 months) of age, and the last tumors were identified at 679 days (22.3 months), with a 50% incidence at 465 days (15.2 months). (B) Tumors predominantly occurred in the abdomen, eye or flank. There was a significant difference between the later onset of eye tumor development (P<0.0086) versus flank or abdomen tumor development.