Skip to main content
. 2009 Dec 9;3(1-2):73–83. doi: 10.1242/dmm.003293

Fig. 6.

Fig. 6.

Loss of KRIT1 increases β-catenin-mediated gene expression. (A) Expression of β-catenin-regulated genes in normal non-involved small intestine (SI) and intestinal adenomas of Krit1+/− ApcMin/+ and Krit1+/+ ApcMin/+ mice. Data shown are the average expression from six mice per group ±S.E.M. Overall P<0.03 by ANOVA, *P<0.05 by Bonferroni post-hoc test compared with Krit1+/+ ApcMin/+ normal SI, #P<0.05 by Bonferroni post-hoc test compared with Krit1+/+ ApcMin/+ adenomas. (B) β-Catenin-regulated gene expression in KRIT1-depleted BAECs. dnTCF, dominant-negative TCF. Data shown are the average expression from five experiments ±S.E.M., P<0.0001 by ANOVA, *P<0.01 by Bonferroni post-hoc testing when compared with negative control siRNA-transfected cells.