Table 2.

 Effect of adding genetic information to global model fit and calibration of risk models to examine indices of model fit

Risk model	Hosmer-Lemeshow P value	Akaike’s information criterion	Likelihood ratio test P value
Cambridge risk score	0.77	1416.1	NA
Framingham offspring risk score	0.42	1319.7	NA
Cambridge risk score plus gene count score	0.85	1414.9	0.07
Framingham offspring risk score plus gene count score	0.52	1319.7	0.17
Cambridge risk score plus genetic risk function score	0.50	1413.4	0.03
Framingham risk score plus genetic risk function score	0.55	1318.9	0.10

NA=not applicable.