Table 4.

 Net reclassification improvement based on addition of gene count score to Cambridge risk score

Predicted diabetes risk (Cambridge risk score)	No of people					Reclassified		Net correctly reclassified (%)
	<5%	5-10%	10-15%	>15%		Increased risk	Decreased risk
Plus gene count score—people without diabetes during follow-up (n=3324)
<5%	2088	105	0	0		167	131	−1.1
5-9.9%	75	581	43	0
10-14.9%	0	42	219	19
≥15%	0	0	14	138
Plus gene count score—people with diabetes during follow-up (n=202)
<5%	60	4	0	0		12	12	0
5-9.9%	3	49	2	0
10-14.9%	0	6	36	6
≥15%	0	0	3	33

Net reclassification improvement −1.1% (95% CI −6.0% to 3.8%); P=0.66.