Table 3.

Publications with histology documented MOM adverse reactions

Reference	Implant	Total cases	Revisions	Histology	When positive histology
Park et al. [21]	Ultima 28 mm THA	169	2 (1.2%)	2 (1.2%)	1—recurrent dislocation 1—osteolysis
Korovessis et al. [15]	Sikomet 28 THA	217	14 (6.5%)	11 (5%)	9—loosening 2—infection
Milosev et al. [20]	Sikomet 28 THA	640	34 (5%)	13 (2%)	11—loosening 2—unexplained pain
Jameson et al. [14]	ASR Total resurfacing	254	8 (3.1%)	3 (1.2%)	3—unexplained pain
Campbell et al. [4]	BHR Total Resurfacing	1500 estimated	Not reported	4 (0.3%)	4—unexplained pain
Engh Jr et al. [current study]	Ultamet 36 THA	945	8 (1%)	3 (0.3%)	1—broken stem, 1—loosening, 1—unexplained pain
Combined reports		3725	66 (2%)	36 (1%)	10—unexplained pain 21—loosening 5—other