Table 4.
Variant | PC1 (74%) |
PC2 (27%) |
||
---|---|---|---|---|
F value | p value | F value | p value | |
CETP Taq1B | 3.38 | 0.006 | 28.01 | <0.001 |
APOE | 8.21 | 0.004 | 13.05 | <0.001 |
a) HDL-C – LDL-C – TC |
Variant | PC1 (84%) |
|
---|---|---|
F value | p value | |
LPL S447X | 4.24 | 0.04 |
b) Weight – Waist – Hip – Triceps and Subscapular skin folds |
Variant | PC1 (72%) |
PC2 (25%) |
||
---|---|---|---|---|
F value | p value | F value | p value | |
APOA5 S19W | 1.52 | 0.218 | 4.29 | 0.039 |
APOA5 −1131C > T | 0.07 | 0.798 | 5.93 | 0.015 |
c) TG – insulin – insulin resistance |
Principal component analysis was performed on three separate clusters. a) HDL-C, LDL-C and TC; b) weight, waist circumference, hip circumference, triceps skin fold and subscapular skin folds; c) TG, insulin and insulin resistanceHOMA. The variance for the first and second principal components (PC1 and PC2) is provided; F and p values are provided for each of the significant variants. LPL, lipoprotein lipase; HDL-C, high-density lipoprotein cholesterol; LDL-C; low-density lipoprotein cholesterol; TC, total cholesterol; CETP, cholesterol ester transfer protein; APO, apolipoprotein and TG, total triglyceride.