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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Mol Microbiol. 2009 Oct 1;74(2):421–435. doi: 10.1111/j.1365-2958.2009.06874.x

Figure 6. Model of temperature-dependent regulation of GmaR expression.

Figure 6

1. OFF: At 37°C, when flagellar motility is OFF, the opposing activities of the MogR repressor and the DegU activator at pfliN-gmaR results in minimal fliN-gmaR transcripts. However, a temperature-dependent, post-transcriptional mechanism inhibits GmaR production.

2. Transition: As the temperature decreases below 37°C, the post-transcriptional mechanism is no longer active, therefore fliN-gmaR transcripts result in GmaR protein production.

3. ON: Once GmaR is expressed at low temperatures, GmaR can remove MogR from the fliN-gmaR promoter, up-regulating transcription of gmaR. Elevated levels of GmaR protein results in the relief of MogR repression from all flagellar motility gene promoters, allowing flagellar motility gene transcription and flagellar motility.