NcRAD23 and NcPNG1 have distinct functions. A and B, growth rates of the indicated strains on medium supplemented with various inhibitors at semipermissive conditions (A), and at permissive conditions (B); bar = 200 μm. C, viability of the indicated strains on medium containing DNA-damaging agents at semipermissive conditions. MMS, methyl methane sulfonate; CPT, camptothecin; 4NQ, 4-nitrochinoline-N-oxide.