FIGURE 5.

PP6 is recruited to TNF receptor complex. A, control (TAB2+/+) and TAB2-deficient (TAB2−/−) fibroblasts were left untreated or stimulated with GST-TNF (1 μg/ml) for 5 min. GST pulldown was performed, and the precipitates were analyzed with anti-PP6 and anti-RIP1 antibodies. B, model.