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. 2003 Nov 10;1:95. doi: 10.1186/1477-7827-1-95

Table 1.

Ovarian TNF and TNF receptors (TNFR) in various animals1)

Species Sources Stages of the estrous cycle2) Method of detection Ref.

F I II III R P
TNF
Cow Follicular fluid + Bioactivity [24]
Theca cells + IHC [25]
Corpus luteum + + MDS/RIA [26]
Corpus luteum + + + + + RT-PCR/ELISA [27]
Corpus luteum + RT-PCR [28]
Pig Corpus luteum + + + + + RT-PCR [29]
Macrophages/CL + + + IHC [30]
EC/CL + + + IHC/Western blot [31]
Human Follicular fluid + ELISA [32]
Granulosa cells + IHC [33]
Theca cells + In situ hybridization [34]
Corpus luteum + + + + IHC [35]
Sheep EC/TC + IF-microscopy [36]
Corpus luteum + Bioactivity [37]
Rat3) Granulosa cells + IHC [25]
Mouse3) GC/TC/CL + + + IHC [38]
TNFR (RI or RII)
Cow GC/TC + RRA/cells [39]
Corpus luteum (RI) + + + + RT-PCR/RRA [27]
Corpus luteum + RRA [28]
EC/CL + RRA/cells [40]
EC/LLC/SLC (RI) + + + + RT-PCR [41]
Pig Granulosa cells + IHC [42]
LLC/SLC + RRA/cells [43]
Corpus luteum + + + + + RRA [44]
Rat3) Ovarian cells (RI, RII) + RT-PCR/RRA [45]

1)Abbreviations; TC: theca cells, GC: granulose cells, EC: endothelial cells, LLC: large luteal cells, SLC: small luteal cells, IHC: immunohistochemistry, RRA: radioreceptor assay. 2)Each stage of the estrous cycle was classified as follows; follicular (F), early-CL (I), mid-CL (II), late-CL (III), regressing CL (R), and pregnancy (P). 3)Each stage of the estrous cycle was classified as follows; estrus (I), metestrus (II), diestrus (III), proestrus (R), and pregnancy or pseudopregnancy (P).