Table 1.
Species | Sources | Stages of the estrous cycle2) | Method of detection | Ref. | |||||
F | I | II | III | R | P | ||||
TNF | |||||||||
Cow | Follicular fluid | + | Bioactivity | [24] | |||||
Theca cells | + | IHC | [25] | ||||||
Corpus luteum | + | + | MDS/RIA | [26] | |||||
Corpus luteum | + | + | + | + | + | RT-PCR/ELISA | [27] | ||
Corpus luteum | + | RT-PCR | [28] | ||||||
Pig | Corpus luteum | + | + | + | + | + | RT-PCR | [29] | |
Macrophages/CL | + | + | + | IHC | [30] | ||||
EC/CL | + | + | + | IHC/Western blot | [31] | ||||
Human | Follicular fluid | + | ELISA | [32] | |||||
Granulosa cells | + | IHC | [33] | ||||||
Theca cells | + | In situ hybridization | [34] | ||||||
Corpus luteum | + | + | + | + | IHC | [35] | |||
Sheep | EC/TC | + | IF-microscopy | [36] | |||||
Corpus luteum | + | Bioactivity | [37] | ||||||
Rat3) | Granulosa cells | + | IHC | [25] | |||||
Mouse3) | GC/TC/CL | + | + | + | IHC | [38] | |||
TNFR | (RI or RII) | ||||||||
Cow | GC/TC | + | RRA/cells | [39] | |||||
Corpus luteum (RI) | + | + | + | + | RT-PCR/RRA | [27] | |||
Corpus luteum | + | RRA | [28] | ||||||
EC/CL | + | RRA/cells | [40] | ||||||
EC/LLC/SLC (RI) | + | + | + | + | RT-PCR | [41] | |||
Pig | Granulosa cells | + | IHC | [42] | |||||
LLC/SLC | + | RRA/cells | [43] | ||||||
Corpus luteum | + | + | + | + | + | RRA | [44] | ||
Rat3) | Ovarian cells (RI, RII) | + | RT-PCR/RRA | [45] |
1)Abbreviations; TC: theca cells, GC: granulose cells, EC: endothelial cells, LLC: large luteal cells, SLC: small luteal cells, IHC: immunohistochemistry, RRA: radioreceptor assay. 2)Each stage of the estrous cycle was classified as follows; follicular (F), early-CL (I), mid-CL (II), late-CL (III), regressing CL (R), and pregnancy (P). 3)Each stage of the estrous cycle was classified as follows; estrus (I), metestrus (II), diestrus (III), proestrus (R), and pregnancy or pseudopregnancy (P).