. Author manuscript; available in PMC: 2010 Jul 1.

Published in final edited form as: Health Psychol. 2009 Jul;28(4):510–518. doi: 10.1037/a0014778

Table 2.

Analysis of Emotional Distress Following BRCA1/2 Mutation Testing

Length of Elapsed Time	Emotional Distress Construct	Gene Mutation Status	Fail-safe			95% CI	Homogeneity test	Moderator Analyses (mixed-effects model unless otherwise noted)
Length of Elapsed Time	Emotional Distress Construct	Gene Mutation Status	k	N	d	95% CI	Homogeneity test	Country	Cancer History
Short	Anxiety	Carrier	9	33	.22^***	.11 to .33	Q(8) = 8.42	Q_B(1) = 1.61^a	Q_B(1) = 1.01^a
		Noncarrier	6	50	−.33^**	−.58 to −.09	Q(5) = 27.13^***	Q_B(1) = 4.62^*	–
		Inconclusive	5	–	−.10	−.26 to .05	Q(4) = 9.62^*	Q_B(1) = .82^a	–
	Cancer-Specific Distress	Carrier	10	109	.27^***	.13 to .41	Q(9) = 28.07^***	Q_B(1) = .05^a	Q_B(1) = .59^a
		Noncarrier	7	69	−.25^**	−.44 to −.06	Q(6) = 41.00^***	Q_B(1) = 11.56^***	–
		Inconclusive	6	41	−.18^*	−.35 to −.01	Q(5) = 28.90^***	Q_B(1) = 2.78	Q_B(1) = 5.68^*
Moderate	Anxiety	Carrier	8	–	−.03	−.18 to .12	Q(7) = 18.16^**	Q_B(1) = 2.91	Q_B(1) = .32
		Noncarrier	6	39	−.22^*	−.40 to −.04	Q(5) = 23.38^***	Q_B(1) = 23.07^***	–
		Inconclusive	7	–	−.12	−.27 to .03	Q(6) = 26.09^***	Q_B(1) = 2.12	–
	Cancer- Specific Distress	Carrier	11	–	−.01	−.14 to .13	Q(10) = 32.62^***	Q_B(1) = 1.40^a	Q_B(1) = 5.07^*
		Noncarrier	9	283	−.42^***	−.65 to −.18	Q(8) = 91.72^***	Q_B(1) = .89	–
		Inconclusive	7	179	−.34^***	−.46 to −.22	Q(6) = 18.94^***	Q_B(1) = .66^a	–
Long	Anxiety	Carrier	4	–	−.03	−.30 to .24	Q(3) = 5.27	–	–
		Noncarrier	3	–	−.06	−.36 to .25	Q(2) = 6.87^*	–	–
		Inconclusive	–	–	–	–	–	–	–
	Cancer-Specific Distress	Carrier	5	–	−.15	−.37 to .07	Q(4) = 14.17^**	–	Q_B(1) = .82^a
		Noncarrier	4	94	−.47^***	−.56 to −.38	Q(3) = 1.54	–	–
		Inconclusive	2	–	−.39^***	−.49 to −.30	Q(1) = .33	–	Q_B(1) = .11.39^***

p ≤ .05;

^**

p ≤.01;

^***

p ≤ .001

Q_B Between-groups heterogeneity for categorical moderators;

Fixed-effects model