Table I.
Treatment | Dose (mg/kg/day) |
Body Weight Change in grams (%) |
---|---|---|
Waterb | 62.3 ± 14.55 (22.5) | |
MPH | 2 | 62.6 ± 10.13 (22.7) |
10 | 62.1 ± 12.29 (22.6) | |
25 | 62.4 ± 15.87 (22.3) | |
EMSb | 100 | −14.3 ± 7.07 c (−4.1) |
Data presented as mean ± standard deviation. Body weight changes were measured from the beginning of dosing to the end of study (28 days for vehicle and MPH-treated rats; 3 days for positive control rats).
Vehicle, deionized water; positive control, EMS (ethyl methanesulfonate).
p<0.05 compared to vehicle control.