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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Environ Mol Mutagen. 2010 Jan;51(1):80–88. doi: 10.1002/em.20515

Table I.

Body Weight Changes for Rats Following Treatment with MPH for 28 Days by Gavagea

Treatment Dose
(mg/kg/day)
Body Weight Change
in grams (%)
Waterb 62.3 ± 14.55 (22.5)
MPH 2 62.6 ± 10.13 (22.7)
10 62.1 ± 12.29 (22.6)
25 62.4 ± 15.87 (22.3)
EMSb 100 −14.3 ± 7.07 c (−4.1)
a

Data presented as mean ± standard deviation. Body weight changes were measured from the beginning of dosing to the end of study (28 days for vehicle and MPH-treated rats; 3 days for positive control rats).

b

Vehicle, deionized water; positive control, EMS (ethyl methanesulfonate).

c

p<0.05 compared to vehicle control.