. Author manuscript; available in PMC: 2011 Jan 1.

Published in final edited form as: Environ Mol Mutagen. 2010 Jan;51(1):80–88. doi: 10.1002/em.20515

Table II.

Cardiac Injury Biomarkers in Serum of Male Wistar Han Rats Treated with MPH for 28 Days By Gavage^a

Dose (mg/kg/day)	TnT		TnI		FABP3
	N^b	ng/ml	n	ng/ml	n	ng/ml
0^c	3	0.132	4	0.035	5	3.82
2	4	0.116	4	0.035	4	1.72
10	4	0.122	5	0.040	4	2.25
25	2	0.119	5	0.028	5	2.04

TnT, serum troponin T; TnI, serum troponin I; FABP3, Fatty Acid Binding Protein-3. Biomarkers were measured using the MesoScale Discovery (MSD®) rat MULTI-SPOT™ cardiac injury panel assay kit and SECTOR Imager 2400 electrochemiluminescence detection platform.

Number of animals providing measurable levels of cardiac biomarkers.

Vehicle control, deionized water.