Figure 1. Characterization of the novel β5-specific proteasome inhibitor NC-005.
A Structures of YU-101 and NC-005. B, C. RPMI-8226 cells were treated with YU-101 and NC-005 for 1h and proteasome activity was measured in cells with ProteasomeGlo assay. Mock-treated cells served as control. Values are averages ± S.E. of two experiments.