Table 2.

Comparisons of CSF neural biomarkers across groups.

	sAPPα	sAPPβ	Aβ1-42	t-tau	p-tau
Overall ANOVA:	< 0.0001	< 0.0001	< 0.0001	< 0.0001	< 0.0001
Post Hoc Comparisons:
ADC vs NA	< 0.001	< 0.001	ns	< 0.05	ns
OIs vs NA	< 0.001	< 0.001	< 0.001	ns	ns
ADC vs OIs	ns	ns	ns	ns	ns
NA vs Cont y	ns	ns	ns	ns	ns
AD vs Cont o	ns	ns	< 0.01	< 0.001	< 0.001
AD vs ADC	< 0.001	< 0.001	ns	< 0.01	< 0.001
Cont y vs Cont o	< 0.05	ns	ns	ns	< 0.01

ns = not significant

* All results were also compared using non-parametric Kruskal-Wallis test that yielded similar results. Statistical tests were also conducted with age adjustment, which did not change any of the results reported above, except for that differences between younger and older controls disappeared.