Figure 5.

Diurnal variation of circadian gene mRNA in livers of C57BL/6J and apoE-/- mice. The experiment has been repeated three times with similar results. The data from three experiments was normalized to GAPDH mRNA and represented as fold increase over CT0 of C57BL/6J mice. (A)*P < 0.05 vs CT0, CT8, CT12 and CT20 in apoE-/- mice on RC or HF diets;^#P < 0.05 vs CT0, CT16 and CT20 in C57BL/6J mice and apoE-/-mice fed with regular chow (B)*P < 0.05 vs CT8, CT12, CT16 and CT20 in apoE-/- mice on RC or HF diets; ^#P < 0.05 vs CT20 in C57BL/6J mice and apoE-/-mice fed with regular chow (C)*P < 0.05 vs CT12 and CT16 in apoE-/- mice on RC or HF diet (D)*P < 0.05 vs CT0, CT8 and CT12 in apoE-/- mice on RC or HF diets