Table 4.
Farm | SPF | Non-SPF | ||||||
---|---|---|---|---|---|---|---|---|
Trait | Direct h2 (s.e.) | Pen effect (s.e.) | Genetic variance × 10-1 | Residual variance × 10-1 | Direct h2 (s.e.) | Pen effect (s.e.) | Genetic variance × 10-1 | Residual variance × 10-1 |
WBC | 0.29 (0.13) | NS | 0.32 | 0.72 | 0.28 (0.11) | NS | 0.21 | 0.55 |
MNL% | 0.09 (0.10) | 0.16 (0.06)* | 0.03 | 2.02 | 0.29 (0.13) | NS | 0.96 | 2.10 |
PMNL% | 0.09 (0.10) | 0.17 (0.06)* | 0.56 | 4.60 | 0.36 (0.14) | NS | 3.00 | 5.20 |
PBML subsets: | ||||||||
CD4+ | 0.78 (0.12) | NS | 187 | 38.3 | 0.57 (0.14) | 0.06 (0.04)* | 147 | 94.1 |
CD8α+ | 0.35 (0.12) | NS | 168 | 306 | 0.60 (0.16) | 0.12 (0.05)* | 215 | 141 |
CD4+CD8α+ | 0.34 (0.15) | NS | 0.58 | 1.10 | 0.37 (0.17) | NS | 0.46 | 0.79 |
CD4+CD8α- | 0.82 (0.17) | NS | 0.95 | 0.19 | 0.45 (0.21) | NS | 0.35 | 0.43 |
CD8αβ+ | 0.48 (0.16) | NS | 0.42 | 0.45 | 0.36 (0.17) | NS | 0.32 | 0.56 |
CD11R1+ total | 0.46 (0.12) | NS | 0.45 | 0.52 | 0.07 (0.08) | 0.34 (0.08)* | 0.09 | 0.78 |
CD11R1+CD8α+ | 0.46 (0.13) | NS | 0.11 | 0.13 | 0.31 (0.16) | NS | 0.73 | 1.60 |
CD11R1+CD8α- | 0.27 (0.11) | 0.13 (0.06)* | 0.39 | 0.88 | 0.27 (0.14) | NS | 0.30 | 0.70 |
γδ+ T cells | 0.46 (0.12) | 0.05 (0.04) | 233 | 279 | 0.30 (0.12) | NS | 141 | 317 |
B cells | 0.41 (0.12) | NS | 0.55 | 0.80 | 0.14 (0.11) | NS | 0.15 | 0.86 |
monocytes | 0.26 (0.11) | 0.11 (0.05)* | 0.42 | 1.00 | 0.26 (0.13) | NS | 0.32 | 0.91 |
CD14+ | 0.04 (0.09) | NS | 0.08 | 1.90 | 0.48 (0.18) | NS | 1.00 | 1.10 |
CD16+ | 0.25 (0.13) | NS | 0.16 | 0.47 | 0.05 (0.09) | 0.09 (0.05)* | 0.04 | 0.83 |
1Traits for which the heritability differed significantly between SPF and non-SPF farms are shown in bold (* p < 0.05). 2 White blood cells expressed as no. cells × 106/mL, PBML sub-sets expressed as proportion of mononuclear leucocytes and antigen density expressed as the number of antibody binding sites per cell (see Materials and Methods).