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. 2010 Jan 18;5(1):e8744. doi: 10.1371/journal.pone.0008744

Figure 1. Generation of Sei1-deficient mice.

Figure 1

(A) Strategy used to eliminate the second exon of Sei1, which contains the entire open reading frame for Sei1. (B) Southern blot confirming the ablation of Sei1 alleles in ES cells. (C) Northern blot confirming the loss of Sei1 transcription in Sei1-null ES. (D) Levels of Sei1 and Sertad2 transcripts in primary MEFs (nā€Š=ā€Š3, per genotype). Values correspond to average and s.d. of the levels relative to actin.