Figure 1. Follow-up of NK cells and NK subsets in whole blood during HBV DNA vaccination.

Absolute values (AV) of NK cells/microL of blood and percentages of NK cells amongst lymphocytes (left panel). Increases in the percentages of CD56^bright after the first and second vaccine injections are shown for 5 patients (middle panel). Follow-up of CD56^bright and CD56^dim populations among NK cells (right panel). Blood samples were collected before the first vaccine injection (M0) and one month after the first (M1), the second (M3), the third (M5) and the fourth (M11) DNA vaccine injections. Analysis performed at M11 included blood samples from the 9 patients whether or not they received the fourth DNA injection. Results are shown as mean ± SE and percentile 95.