Table.
Children with Sickle Cell Anemia and Acute Silent Cerebral Infarction
| Case | Age (years) |
Sex | Clinical Presentation | Hgb (g/dl) Presentation |
Hgb (g/dl) Baseline |
MRI | MRA | Follow up MRI |
|---|---|---|---|---|---|---|---|---|
| 1 | 5 | M | Transient L hemiparesis | 3.4 | 7.8 | Multiple bilateral deep white matter acute SCI |
Normal | Corresponding SCI |
| 2 | 3.5 | M | Transient ataxia | 7.1 | CT | Single acute SCI R deep white matter |
Abnormal | Corresponding SCI |
| 3 | 9.5 | F | Headache and transient gait abnormality 1 month after L hemisphere overt stroke |
8.4 | CT | Single acute SCI L precentral gyrus |
Abnormal | Not Done |
| 4 | 11 | F | Severe headache following transfusion for aplastic crisis |
2.7 | 8.3 | Multiple bilateral cortical and deep white matter acute SCI |
Abnormal | Corresponding SCI |
| 5 | 9 | M | Vertebral artery laceration from dog mauling |
3.4 | 7.1 | Bilateral watershed infarct | Normal | Not done |
| 6 | 4 | F | Altered mental status, ataxia, respiratory arrest from aplastic crisis |
2.2 | 7.2 | Acute SCI in R mesencephalon & lingula of R Occipital lobe |
Normal | Corresponding SCI |
| 7 | 6 | M | Asymptomatic. Fever and chest pain 2 weeks prior |
8.5 | 7.7 | Acute SCI in L temporal lobe | Abnormal | Not done |
Abbreviations: SCI= silent cerebral infarct, L=left, R=right, CT=chronic transfusion