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. 2010 Jan;129(1):28–40. doi: 10.1111/j.1365-2567.2009.03155.x

Figure 1.

Figure 1

Double single-chain fragment variable antibodies (dscFv) anti-CD33/anti-CD3 induced proliferation of T cells in a dose-dependent manner. Antigen-immobilized dscFv anti-CD33/anti-CD3 at various concentrations or control antibody fusion proteins single-chain fragment variable (scFv) anti-CD33, sc CD80/anti-CD33 and sc CD86/anti-CD33 (10 μg/ml) were used to stimulate T cells for 3 days. Cells were then pulsed for 16 hr before harvesting. Mean values of triplicate cultures are shown. Results are representative of three independent experiments. c.p.m., counts per minute.