Figure 3.
Identification of specific interactions when coated nanoparticles were applied across the chip with 36 proteins immobilized (at least three interactions shown, as dashed or dotted lines). (a) Leucocyte-associated immunoglobulin-like receptor 1 (LAIR-1)-coated nanoparticles bound to leucocyte immunoglobulin-like receptor subfamily B member 4 (Lilrb4) proteins (solid line). (b) poliovirus receptor (PVR)-coated nanoparticles bound to TACTILE protein (solid line). (c) Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1)-coated nanoparticles bound to CEACAM8 proteins (solid line) more strongly than to itself (dashed line) and the other proteins (dots and long dashes). (d) The reverse interaction where CEACAM8-coated nanoparticles bound to CEACAM1 protein (solid line) with trace binding to itself (dashed line) compared with other proteins (dots and long dashes).