Table 1.
Thirty-two proteins immobilized on surfaces of the ProteOn™ array system, besides the four unlisted members of the mCD200R family (mCD200RLa, mCD200RLb, mCD200RLc and mCD200RLe), are listed in the first column and the proteins coated on the applied nanoparticles are listed in the first row
| CEACAM1 | CEACAM8 | TACTILE (CD96) | CD85 | CD85C | CD85E | CD85H | CD85K (LILRB4) | CRTAM | LAIR1 (CD305) | CD226 (DNAM) | CD200 | PVR (CD155, NECL5) | NECL1 | NECL2 | All other proteins | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TREM1 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| TREM2 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| CD200 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| CEACAM1 (CD66) | ++ | +++ | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| CEACAM5 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| CEACAM6 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| CEACAM8 (CD67) | +++ | + | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| NCR3 (CD337) | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| TACTILE (CD96) | – | – | – | – | – | – | – | – | – | – | – | – | ++ | – | – | – |
| PVR (CD155, NECL5) | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| CD226 (DNAM) | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| NECL1 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| NECL2 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| PSG (CD66F) | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| mGPNMB | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| CD85 | – | – | – | – | – | – | – | + | – | – | – | – | – | – | – | – |
| CD85C | – | – | – | – | – | – | – | + | – | – | – | – | – | – | – | – |
| CD85E | – | – | – | – | – | – | – | + | – | – | – | – | – | – | – | – |
| CD85H | – | – | – | – | – | – | – | + | – | – | – | – | – | – | – | – |
| CD85K (LILRB4) | – | – | – | – | – | – | – | + | – | +++ | – | – | – | – | – | – |
| CD83 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| CMRF35 (CD300C) | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| CRTAM | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| CD5 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| CD6 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| CD72 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| TOSO | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| LAIR1 (CD305) | – | – | – | – | – | – | – | +++ | – | – | – | – | – | – | – | – |
| ESAM | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| CD99 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| mMAIR | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| CD73 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
The responses are summarized: ‘–’: no specific binding; ‘+’: weak but specific binding; ‘+++’: strong and specific binding. (If not noted, all the proteins were constructed from human genes).