. 2009 Feb 22;3(1):63–68. doi: 10.1007/s12105-009-0103-8

Table 2.

Inter- and intra-rater reliability for dysplasia grades in oral and laryngeal precancerous lesions

Authors	Grading system	% agreement or Kappa inter-rater	% agreement or Kappa intra-rater
McLaren et al. (2000) [8]	VC 5 grade WHO 2 grades mild versus severe dysplasia	K 0.32
		K 0.52
		K 0.52
Kujan et al. (2006) [9]	OC 2 grades 5 grade WHO	K 0.50
Kujan et al. (2006) [9]	OC 2 grades 5 grade WHO	Ks 0.22, Kw 0.63
Karabulut et al. (1995) [10]	OC 5 grade WHO	K 0.27–0.45 (49–59%)
Abbey et al. (1995) [11]	OC 4 grade WHO dysplasia versus none	50.5%,	50.8%
Abbey et al. (1995) [11]	OC 4 grade WHO dysplasia versus none	81%	80.3%
Fischer et al. 2004 [12]	OC 5 grade WHO attending pathologist versus committee	K 0.59
Brothwell et al. 2003 [13]	OC 5 grade WHO dysplasia versus none modal score standard	Kw 0.74	Ks 0.22–0.78
Brothwell et al. 2003 [13]	OC 5 grade WHO dysplasia versus none modal score standard	K 0.51	Ks 0.22–0.78

VC = vocal cords, OC = oral cavity; 2 grades––low grade dysplasia/high grade dysplasia; Ljubljana––simple hyperplasia, abnormal hyperplasia, atypical hyperplasia, carcinoma in situ; 5 grade WHO––no, mild, moderate, severe dysplasias and carcinoma in situ; 4 grade merges severe dysplasia with CIS