Table 1.
Clinicopathological findings in 22 basaloid squamous cell carcinomas of the larynx and hypopharynx
| Case | A/S | Origin | Basal C | VL inv | Lymph node | Level | Staging | Follow-up (months) | Loc Rec | Dist Met | SPT |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 49/M | Transglottic | +++ | Yes | pN1 | III | 3 | 10-DOD | − | − | − |
| 2 | 62/M | Vallecula | +++ | No | pN2 B | III | 4 | 35-DOD | − | − | − |
| 3 | 42/M | Left piriform | +++ | Yes | pN2 B | III | 4 | 18-DOD | − | − | − |
| 4 | 63/M | Supraglottic | +++ | Yes | pN1 B | III | 3 | 25-DOD | − | − | Bronchus |
| 5 | 63/M | Supraglottic | + | Yes | pN1 B | III | 3 | 15-DOD | − | − | − |
| 6 | 50/M | Supraglottic | + | No | − | − | 2 | 48-AwD | − | − | − |
| 7 | 61/M | Supraglottic | + | No | − | − | 3 | 39-AwD | − | − | − |
| 8 | 54/M | Supraglottic | +++ | No | pN2b B | III/IV | 4 | 14-DOD | +++ | Bone | − |
| 9 | 56/M | Supraglottic | +++ | No | − | − | 1 | 71-AwD | − | − | − |
| 10 | 75/M | Supraglottic | +++ | No | − | − | 1 | 36-AwD | − | − | − |
| 11 | 58/M | Supraglottic | +++ | No | pN2b B | III | 4 | 6-DOD | +++ | − | − |
| 12 | 65/M | Vallecula | +++ | No | pN2c B | III/IV | 4 | 45-DOD | +++ | Lung | − |
| 13 | 52/M | Supraglottic | +++ | No | pN1 | Delph (mi) | 4 | 74-AwD | − | − | − |
| 14 | 73/M | Glottic | +++ | No | − | − | 4 | 20-AwD | − | − | − |
| 15 | 41/F | Supraglottic | +++ | No | pN1 B | III/IV (mi) | 4 | 26-DOD | Tracheostoma | Lung | |
| 16 | 75/M | Supraglottic | + | No | − | − | 3 | 12-AwD | − | − | − |
| 17 | 61/M | Left piriform | + | No | pN2B E-E | III/IV | 2 | 13-DOD | +++ | − | − |
| 18 | 57/M | Left piriform | +++ | No | pN1 E-E B | III | 3 | 83-AwD | − | − | − |
| 19 | 62/M | Left pirifomr | +++ | Yes | pN2b E-E B | III | 4 | 8-DOD | − | − | − |
| 20 | 64/M | Left piriform | +++ | No | pN1 E-E B | III | 3 | 11-AwD | − | − | − |
| 21 | 62/M | Left piriform | +++ | No | pN2b E-E B | II/IV | 4 | 3-DOD | − | − | Bronchus |
| 22 | 66/M | Left piriform | +++ | No | pN2c E-E B | II/IV | 4 | 17-AWD | − | − | Sinonasal |
A/S: age and sex, Basal C: basal component (+++ abundant, + scarce), VL inv: vascular-lymphatic invasion, Lymph node: nodal status, Level: level of metastatic seed in neck dissection, Loc Rec: local recurrences, Dist Met: distant metastases, SPT: second primary tumour, B: biphasic (basaloid and squamous) tumour, E-E: extracapsular extension, delph: delphian node, (mi): microscopic, DOD: died of disease, AwD: alive without disease, AWD: alive with disease