Fig. 4.

TreeView diagrams of genes identified in the second analysis based on the ability to distinguish aggressive from non-aggressive tumors (t-test, P < 0.01) for (a) oropharynx (66 genes), (b) oral cavity (176 genes), and (c) larynx/hypopharynx (95 genes). Each row in the TreeView diagram represents a single gene in the signature; each column represents a single HNSCC primary tumor. Red indicates increased expression of the gene in a tumor relative to the site-specific tumor pool; green indicates decreased expression. Genes for which no data are reported for a given tumor are indicated in grey. Division of the aggressive versus non-aggressive tumors for each site are indicated below each TreeView diagram