Fig. 6.

Network of oropharyngeal HNSCC discriminating aggressive and non aggressive tumors. The median values for aggressive (a) and non aggressive (b) oral cavity HNSCC were subjected to analysis by IPA. The highest scoring network for aggressive (41, 18 focus molecules) and non aggressive (41, 18 focus molecules) tumors are shown. Colored symbols are focus molecules where red indicates increased expression and green represents decreased expression. The intensity of each color reflects the expression of the gene relative to the tumor pool reference. A legend for the shapes and lines is available in the tutorial section at www.ingenuity.com