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. Author manuscript; available in PMC: 2010 Aug 1.
Published in final edited form as: Nat Rev Microbiol. 2009 Aug;7(8):555–567. doi: 10.1038/nrmicro2182

Figure 6. S. epidermidis as a commensal and infectious microorganism.

Figure 6

Determinants that are believed to contribute to both S. epidermidis colonization and pathogenesis are shown. In animal models, only the roles of PNAG/PIA, PGA, and the MSCRAMM SdrG in infection have been demonstrated. Other roles are based on in vitro experiments and environmental challenges during colonization and infection. Not shown are regulators such as agr or sigB that control many of the depicted determinants and may thus also have important functions during both S. epidermidis lifestyles.