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Sodium nitroprusside (SNP) induced relaxations of phenylephrine-preconstricted aortic rings in the absence or presence of indomethacin (INDO, 5 × 10−6 M). SHR, spontaneously hypertensive rats (A); Z0.5, SHR treated with zofenopril 0.5 mg·kg−1 per day (B); Z10, SHR treated with zofenopril 10 mg·kg−1 per day (C).
