Table 1.
Parameter | SHR | Z0.5 | Z10 | WKY |
---|---|---|---|---|
BW (g) | 402 ± 3# | 414 ± 3 | 402 ± 6 | 538 ± 14 |
LVW (mg) | 1092 ± 12# | 1080 ± 15 | 874 ± 15* | 941 ± 34 |
LVW/BW | 2.82 ± 0.03# | 2.68 ± 0.04* | 2.22 ± 0.04* | 1.86 ± 0.03 |
KW (mg) | 1241 ± 15# | 1221 ± 27 | 1213 ± 20 | 1421 ± 37 |
KW/BW | 3.20 ± 0.05# | 3.06 ± 0.06* | 3.07 ± 0.05* | 2.81 ± 0.10 |
Values are means ± SEM.
P < 0.05 compared with SHR;
P < 0.05 compared with WKY.
SHR, spontaneously hypertensive rats; Z0.5, SHR treated with zofenopril 0.5 mg·kg−1 per day; Z10, SHR treated with zofenopril 10 mg·kg−1 per day; WKY, Wistar-Kyoto rats; BW, body weight; LVW, left ventricular weight; KW, kidney weight.