Table 3.
Wall geometry of small intrarenal resistance arteries
| Parameter | SHR | Z0.5 | Z10 | WKY |
|---|---|---|---|---|
| L (µm) | 11.8 ± 0.7# | 14.1 ± 1.0* | 14.5 ± 0.9* | 21.1 ± 2.6 |
| Wm (µm) | 11.6 ± 0.5# | 11.4 ± 0.5 | 10.1 ± 0.4* | 8.9 ± 0.5 |
| Wm/L | 1.06 ± 0.06# | 0.91 ± 0.07 | 0.77 ± 0.06* | 0.47 ± 0.05 |
| CSAm (µm2) | 793 ± 60 | 893 ± 67 | 761 ± 59 | 664 ± 98 |
Values are means ± SEM.
*
P < 0.05 compared with SHR;
#
P < 0.05 compared with WKY.
SHR, spontaneously hypertensive rats; Z0.5, SHR treated with zofenopril 0.5 mg·kg−1 per day; Z10, SHR treated with zofenopril 10 mg·kg−1 per day; WKY, Wistar-Kyoto rats; L, lumen; Wm, medial thickness; CSAm, medial cross-sectional area.