Figure 2.

Model-free linkage analysis of wellness by using GH-PLUS. Map position is in Kosambi centimorgans. The −log₁₀ P was calculated by using P values generated by GH-PLUS on the assumption that the NPL score is standard normally distributed. A −log₁₀ P of 4.0 corresponds asymptotically to a logarithm of odds score of 3.0. Only mentally healthy individuals 45 years of age or older were classified as being well (see text). (A) −log₁₀ P for markers on chromosome 4p: dotted line, pedigree 110 only; and solid line, pedigrees 110, 210, 310, and 410. (B) −log₁₀ P for markers on chromosome 4q: dotted line, pedigree 110 only, and solid line, pedigrees 110, 210, 310, and 410.