Table 2.

Percentages of skeletal alterations observed in newborn Asxl1 and Asxl1; Cbx2 compound mutants.

	Genotype
		+/+		Asxl1/+		Asxl1/Asxl1		+;Cbx2/+		Asxl1/+;Cbx2/+	Asxl1/Asxl1; Cbx2/+
		n=11		n=19		n=14		n=6		n=11	n=2
Phenotype
C1 to exoccipital		0		0		14		0		9		0
C2 to C1	9		32		93		67		82		100
C7 to T1	0		0		14		17		0		0
Abnormal scapula	0		0		0		0		9		0
T7 to T8	0		0		0		0		9		50
Offset ribs	0		0		0		0		27		100
Abnormal xiphoid process	9		5		50		33		64		100
T13 to L1	9		26		64		17		45		100

Penetrance of the skeletal abnormalities expressed as a percentage of the embryos analyzed for each genotype. Abbreviations and phenotypes are described in the text. The expressivity of the C1 to occipital transformation is much more severe in Asxl1; Cbx2 double mutants than in Asxl1 homozygotes (see Fig. 4C).