Table 6.
Diagnostic characteristics of the per cent predicted method, using the percentile method as a reference standard using Crapo et al (5–7) and Gutierrez et al (12) equations for men (n=2176)
Parameter |
Crapo et al |
Gutierrez et al |
||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Sen, % | Spe, % | PPV, % | NPV, % | LR+ | LR− | Sen, % | Spe, % | PPV, % | NPV, % | LR+ | LR− | |
FEV1 | 93 | 97 | 98 | 91 | 32 | 0.07 | 98 | 90 | 92 | 97 | 9 | 0.03 |
FVC | 99 | 90 | 84 | 99 | 10 | 0.01 | 95 | 94 | 93 | 96 | 17 | 0.05 |
RV↓ | 100 | 92 | 50 | 100 | 13 | 0.00 | 100 | 87 | 33 | 100 | 7 | 0.00 |
RV↑ | 82 | 100 | 100 | 91 | 2264 | 0.18 | 90 | 92 | 98 | 96 | 107 | 0.11 |
TLC↓ | 93 | 100 | 97 | 99 | 189 | 0.07 | 90 | 99 | 97 | 97 | 93 | 0.11 |
TLC↑ | 94 | 100 | 98 | 99 | 357 | 0.06 | 85 | 100 | 97 | 98 | 343 | 0.15 |
DLco | 88 | 97 | 97 | 88 | 32 | 0.12 | 99 | 91 | 82 | 99 | 11 | 0.02 |
↓ Below normal;
↑ Above normal, for all other parameters, only below normal are presented; DLco Diffusing capacity of the lung for carbon monoxide; FEV1 Forced expiratory volume in 1 s; FVC Forced vital capacity; LR+ Positive likelihood ratio; LR– Negative likelihood ratio; NPV Negative predictive value; PPV Positive predictive value; RV Residual volume; Sen Sensitivity; Spe Specificity; TLC Total lung capacity