Table 3.
PP2A single allele association with breast cancer risk
| Heterozygous | Homozygous Variant | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Gene SNP |
Minor Allele |
No. of Subjects | Odds Ratio |
P Value | No. of Subjects | Odds Ratio |
P Value | ||
| Cases | Controls | Cases | Controls | ||||||
| PPP2R1A | |||||||||
| rs6509626 | T | 72 | 164 | 0.86 | 0.33 | 20 | 29 | 1.26 | 0.43 |
| rs10420138 | C | 213 | 443 | 1.02 | 0.91 | 99 | 160 | 1.35 | 0.07 |
| rs1560092 | A | 215 | 492 | 0.61 | 0.0003 | 83 | 187 | 0.62 | 0.01 |
| rs11881878 | A | 103 | 177 | 1.25 | 0.12 | 10 | 11 | 1.88 | 0.15 |
| rs7251605 | A | 146 | 287 | 1.05 | 0.71 | 26 | 27 | 1.96 | 0.02 |
| rs10520481 | T | 67 | 108 | 1.28 | 0.14 | 5 | 2 | 5.21 | 0.05 |
| rs10412613 | G | 198 | 409 | 0.92 | 0.51 | 54 | 108 | 0.93 | 0.70 |
| rs10403202 | A | 65 | 142 | 0.88 | 0.43 | 3 | 2 | 3.25 | 0.20 |
| rs755533 | A | 200 | 400 | 1.07 | 0.58 | 59 | 89 | 1.44 | 0.06 |
| rs2016457 | T | 158 | 337 | 0.91 | 0.47 | 38 | 52 | 1.55 | 0.05 |
| rs8100500 | T | 116 | 241 | 0.95 | 0.71 | 14 | 10 | 2.90 | 0.01 |
| rs4802905 | C | 108 | 193 | 1.20 | 0.18 | 6 | 8 | 1.54 | 0.43 |
| rs9917069 | T | 156 | 331 | 0.87 | 0.26 | 18 | 49 | 0.67 | 0.16 |
| rs7259175 | T | 83 | 203 | 0.76 | 0.05 | 8 | 6 | 2.66 | 0.07 |
| PPP2R2A | |||||||||
| rs1010406 | A | 65 | 114 | 1.15 | 0.42 | 2 | 7 | 0.57 | 0.48 |
| rs9650418 | T | 226 | 464 | 0.88 | 0.36 | 92 | 198 | 0.82 | 0.25 |
| rs1564577 | C | 211 | 436 | 0.94 | 0.63 | 74 | 151 | 0.93 | 0.66 |
| rs7838409 | G | 142 | 340 | 0.73 | 0.01 | 28 | 54 | 0.96 | 0.87 |
| rs17055142 | T | 60 | 138 | 0.82 | 0.26 | 1 | 4 | 0.46 | 0.49 |
| rs1594829 | A | 154 | 329 | 0.93 | 0.59 | 29 | 46 | 1.17 | 0.53 |
| rs2046223 | T | 201 | 427 | 0.92 | 0.51 | 58 | 105 | 1.05 | 0.80 |
| rs2046222 | T | 45 | 72 | 1.25 | 0.27 | 0 | 1 | 0.00 | 0.99 |
| rs2164027 | C | 191 | 386 | 1.01 | 0.96 | 51 | 83 | 1.23 | 0.30 |
| rs12682345 | C | 174 | 378 | 0.92 | 0.51 | 45 | 68 | 1.28 | 0.25 |
| rs17309613 | C | 34 | 88 | 0.77 | 0.23 | 1 | 0 | > 99 | 0.98 |
| rs17055163 | G | 115 | 211 | 1.12 | 0.41 | 10 | 15 | 1.35 | 0.46 |
| PPP2R5E | |||||||||
| rs1152449 | C | 177 | 360 | 1.01 | 0.95 | 43 | 62 | 1.48 | 0.07 |
| rs4902233 | T | 151 | 292 | 1.04 | 0.78 | 6 | 9 | 1.29 | 0.63 |
| rs1255641 | T | 115 | 216 | 1.08 | 0.58 | 7 | 17 | 0.78 | 0.60 |
| rs8009130 | T | 102 | 198 | 1.07 | 0.65 | 10 | 10 | 2.08 | 0.10 |
| rs7144300 | C | 108 | 244 | 0.88 | 0.35 | 17 | 20 | 1.72 | 0.10 |
| rs1255625 | G | 120 | 254 | 0.95 | 0.71 | 18 | 23 | 1.65 | 0.12 |
| rs4902230 | A | 118 | 237 | 0.99 | 0.96 | 13 | 24 | 1.02 | 0.96 |
| rs11158493 | T | 152 | 300 | 1.01 | 0.97 | 23 | 49 | 0.93 | 0.78 |
| rs1951212 | A | 145 | 292 | 0.98 | 0.87 | 20 | 44 | 0.89 | 0.67 |
| rs8005767 | G | 55 | 98 | 1.20 | 0.30 | 6 | 3 | 4.10 | 0.05 |
| rs11846721 | C | 96 | 190 | 1.05 | 0.72 | 9 | 11 | 1.60 | 0.30 |
| rs10140679 | T | 173 | 347 | 1.02 | 0.86 | 44 | 75 | 1.19 | 0.42 |
| rs4147456 | T | 94 | 178 | 1.11 | 0.48 | 8 | 11 | 1.42 | 0.46 |
| rs2180493 | A | 68 | 109 | 1.32 | 0.10 | 6 | 8 | 1.54 | 0.43 |
| rs10145042 | C | 90 | 177 | 1.04 | 0.79 | 7 | 9 | 1.49 | 0.43 |
| rs1951210 | A | 76 | 134 | 1.20 | 0.27 | 2 | 7 | 0.67 | 0.62 |
| rs11158490 | G | 132 | 229 | 1.22 | 0.15 | 14 | 32 | 0.99 | 0.97 |
| rs6573514 | A | 76 | 126 | 1.26 | 0.16 | 3 | 11 | 0.60 | 0.43 |
| rs10135846 | G | 74 | 123 | 1.26 | 0.16 | 4 | 4 | 2.73 | 0.19 |
| rs7146445 | C | 82 | 136 | 1.26 | 0.14 | 4 | 6 | 1.64 | 0.46 |