Table 4.

Effects of PP2A gene haplotypes on breast cancer risk

Gene				Copies of Haplo- type	Odds ratio	95% Confidence Interval	P value
	Haplotype	Cases	Controls
PPP2R1A
	C
A:	Recessive	298	675	≤1	1
	risk	151	211	2	1.63	1.3 – 2.1	0.0002*
	CTAGGCA
B:	Dominant	252	344	0	1
	protection	87	209	≥1	0.555	0.41 – 0.76	0.0002*
PPP2R2A
	A
C:	Recessive	170	393	≤1	1
	Risk	280	497	2	1.32	1.0 – 1.7	0.022
	G
D:	Dominant	280	497	0	1
	protection	170	393	≥1	0.759	0.60 – 0.96	0.022
PPP2R5E
	GCT
E:	Dominant	393	804	0	1
	risk	55	82	≥1	1.42	1.0 – 2.0	0.063
	GA
F:	Recessive	144	245	≤1	1
	protection	304	637	2	0.776	0.6 – 1.0	0.057

^*Permuted P = 0.003