Skip to main content
. Author manuscript; available in PMC: 2010 Jul 1.
Published in final edited form as: Am J Surg Pathol. 2009 Jul;33(7):1006–1015. doi: 10.1097/PAS.0b013e31819f57e9

Table 3.

Phenotypic markers in non-goblet columnar epithelium from patients with columnar metaplasia of the distal esophagus either with or without goblet cells

Marker Patients with columnar metaplasia with goblet cells (Barrett’s Esophagus) Patients with columnar metaplasia without goblet cells Gastric Controls
LDGC N=25 HDGC N=34 Total N=59 N=30 N= 19
MUC5AC 25 (100%) 34 (100%) 59 (100%) 30 (100%) 19 (100%)
MUC2 18 (72%)c 32 (94%)c 50 (85%) 0 (0%) 0
Das-1 21 (84%) 32 (94%) 53 (90%) 9 (30%) 0
Villin 23 (92%) 33 (97%) 56 (95%) 5 (17%) 0
CDX-2 24 (96%) 34 (100%) 58 (98%) 13 (43%) 0
Ki67 12 (48%)a 25 (74%)b 37 (63%) 5 (17%)a,b 0

LDGC = low density goblet cells, HDGC = high density goblet cells, N = number of patients

a

p<0.02

b

p<0.0007

c

p<0.03