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. Author manuscript; available in PMC: 2010 Jul 1.
Published in final edited form as: Am J Surg Pathol. 2009 Jul;33(7):1006–1015. doi: 10.1097/PAS.0b013e31819f57e9

Table 4.

Phenotypic markers in non-goblet columnar epithelium in areas of mucosa either with or without goblet cells in patients with Barrett’s esophagus

Marker Patients with columnar metaplasia with goblet cells (Barrett’s Esophagus)
LDGC N = 25 HDGC N = 34
CM-NG CM-WG CM-NG CM-WG
MUC 5AC 25 (100%) 25 (100%) 34 (100%) 34 (100%)
MUC 2 2 (8%)a 18 (72%) a 0 (0%) b 32 (94%) b
Das-1 8 (32%) c 17 (68%) c 13 (38%) d 32 (94%) d
Villin 7 (28%) e 23 (92%) e 12 (35%) f 33 (97%) f
CDX-2 10 (40%) g 24 (96%) g 9 (26%) h 34 (100%) h
Ki67 2 (8%) i, k 11 (44%) i 10 (29%) j, k 19 (56%) j

LDGC = low density goblet cells, HDGC = high density goblet cells, CM-NG = columnar mucosa -no goblet cells, CM-WG = columnar mucosa -with goblet cells

a

p<0.0005

b

p<0.0005

c

p<0.02

d

p<0.0005

e

p<0.0005

f

p<0.0005

g

p<0.000

h

p<0.0005

i

p<0.009

j

p<0.04

k

p=0.051