Table 1.
Baseline Characteristics of RRISK Cohort and factors associated with Irritable Bowel Syndrome
| Characteristics | No IBS N (%) |
IBS N (%) |
Multivariate OR (95% CI) |
P† |
|---|---|---|---|---|
| N | 1903 | 204 | ||
| Demographics | ||||
| Age, mean +/− SD‡ | 56 ± 9 | 56 ± 9 | 0.9 (0.8 – 0.9) | <0.01 |
| Race | <0.01 | |||
| Caucasian | 878 (46) | 125 (61) | Reference | |
| African-American | 349 (18) | 33 (16) | 0.6 (0.4 – 0.9) | |
| Asian | 332 (17) | 13 (6) | 0.3 (0.1 – 0.5) | |
| Latina and other | 344 (18) | 33 (16) | 0.6 (0.4 – 0.9) | |
| Medical/Surgical History | ||||
| Diabetes | 151 (8) | 23 (11) | 1.8 (1.1 – 3.1) | 0.02 |
| Hysterectomy | 401 (21) | 74 (36) | 2.0 (1.4 – 2.9) | <0.01 |
| Urinary incontinence surgery | 42 (2) | 8 (4) | 0.5 (0.2 – 1.4) | 0.17 |
| Pelvic organ prolapse surgery | 57 (3) | 18 (9) | 2.5 (1.1 – 5.5) | 0.02 |
| Colon surgery | 60 (3) | 18 (9) | 2.5 (1.3 – 4.8) | <0.01 |
| Pelvic Floor Disorders | ||||
| Urinary urgency, ≥ weekly | 446 (30) | 72 (40) | 1.4 (1.0 – 1.9) | 0.06 |
| Any urinary incontinence | 1346 (71) | 170 (83) | 1.6 (0.8 – 3.0) | 0.18 |
| Never | 557 (29) | 34 (17) | Ref | 0.12 |
| Less than monthly | 552 (29) | 57 (28) | 1.4 (0.7 – 2.9) | |
| Monthly | 265 (14) | 39 (19) | 1.9 (0.9 – 3.8) | |
| Weekly | 308 (16) | 33 (16) | 1.2 (0.6 – 2.5) | |
| Daily | 221 (12) | 41 (20) | 2.0 (1.0 – 4.3) | |
| Symptomatic pelvic organ prolapse in last 12 months |
93 (5) | 25 (12) | 2.4 (1.4 – 4.1) | <0.01 |
IBS = Irritable Bowel Syndrome; OR = Odds Ratio; CI = Confidence Interval; SD = Standard Deviation
Variables not included in this table include, history of cancer, postmenopausal, tobacco use, oophorectomy because statistical significance of each was p>0.2 in univariate analysis
†
Based on a multivariate logistic regression model that included all variables shown in the table with p-values that remained less than 0.20 after adjustment.
‡
Odds ratio for age is reported per 5 years.