Table 1.
Demographic and viral characteristics and liver abnormalities of 634 subjects seropositive for hepatitis B surface antigen n (%)
| Variables | Genotype B (n = 199) | Genotype C (n = 411) | Others (n = 24)1 | P value2 |
| Age (yr)3 | 42.1 ± 13.0 | 41.3 ± 12.8 | 43.8 ± 12.8 | 0.493 |
| Gender | ||||
| Male | 116 (58.3) | 228 (55.5) | 16 (66.7) | |
| Female | 83 (41.7) | 183 (44.5) | 8 (33.3) | 0.511 |
| ALT (log10 U/L)3 | 1.4 ± 0.3 | 1.4 ± 0.3 | 1.4 ± 0.2 | 0.238 |
| ≤ 45 U/L | 174 (87.4) | 373 (90.8) | 23 (95.8) | |
| > 45 U/L | 25 (12.6) | 38 (9.2) | 1 (4.2) | 0.207 |
| HBeAg | ||||
| Negative | 186 (93.5) | 385 (93.7) | 24 (100.0) | |
| Positive | 13 (6.5) | 26 (6.3) | 0 | 0.922 |
| HBV DNA levels (log10 copies/mL)3 | 3.7 ± 1.7 | 3.5 ± 1.7 | 3.1 ± 1.1 | 0.194 |
| < 4 | 151 (75.9) | 347 (84.4) | 23 (95.8) | |
| ≥ 4 | 48 (24.1) | 64 (15.6) | 1 (4.2) | 0.011 |
| Fatty liver | ||||
| Yes | 16 (8.0) | 24 (5.8) | 2 (8.3) | |
| No | 183 (92.0) | 387 (94.2) | 22 (91.7) | 0.303 |
| Cirrhosis status | ||||
| Normal | 183 (92.0) | 350 (85.2) | 19 (79.2) | |
| Probable cirrhosis4 | 16 (8.0) | 61 (14.8) | 5 (20.8) | 0.018 |
1
23 cases for genotype mixture, 1 case for genotype D;
2
Genotype C vs genotype B;
3
mean ± SD;
4
Ultrasonographic cirrhosis and cirrhosis-like ultrasonographic abnormalities (ultrasonographic score ≥ 5). ALT: Alanine aminotransferase; HBeAg: Hepatitis B e antigen; HBV: Hepatitis B virus.