Table 2.
Univariate and multivariate regression analyses for the risk factors of probable liver cirrhosis in the 595 HBeAg negative subjects infected with HBV
| Variables | Controls (n = 513) | Cases (n = 82) | OR (95% CI) | AOR (95% CI) |
| Age (yr) | ||||
| < 45 | 284 (55.4) | 31 (37.8) | ||
| ≥ 45 | 229 (44.6) | 51 (62.2) | 2.04 (1.26-3.29) | 1.81 (1.10-2.99) |
| Sex | ||||
| Female | 235 (45.8) | 25 (30.5) | ||
| Male | 278 (54.2) | 57 (69.5) | 1.93 (1.17-3.18) | 1.74 (1.03-2.95) |
| ALT (U/L) | ||||
| ≤ 45 | 473 (92.2) | 66 (80.5) | ||
| > 45 | 40 (7.8) | 16 (12.9) | 2.87 (1.52-5.41) | 2.98 (1.48-5.99) |
| Viral load (Log10 copies/mL) | ||||
| < 4 | 432 (84.2) | 67 (81.7) | ||
| ≥ 4 | 81 (15.8) | 15 (18.3) | 1.19 (0.65-2.19) | 1.06 (0.54-2.08) |
| Genotype | ||||
| B | 170 (34.4) | 16 (20.8) | ||
| C | 324 (65.6) | 61 (79.2) | 2.00 (1.12-3.58) | 2.30 (1.26-4.19) |
AOR: Adjusted odds ratio; OR: Odds ratio.