Table 1.
Positive selection of 5C.C7 TCR transgenic thymocytes
| Experiment | DP
|
CD4 SP
|
CD8 SP
|
||||
|---|---|---|---|---|---|---|---|
| +/+ or +/− | −/− | +/+ or +/− | −/− | +/+ or +/− | −/− | ||
| Eb/b | 1* | 80.0% | 79.8 | 7.2 | 9.2 | 1.7 | 2.2 |
| 2 | 87.1 | 87.6 | 2.4 | 3.7 | 2.9 | 2.1 | |
| 3 | 79.7 | 67.5 | 3.9 | 4.8 | 2.7 | 3.0 | |
| Eb/k | 1* | 43.3 | 20.3 | 47.8 | 70.4 | 4.1 | 4.0 |
| 2 | 50.3 | 25.5 | 37.2 | 61.3 | 7.5 | 4.3 | |
| 3 | 45.4 | 24.9 | 44.3 | 65.2 | 6.6 | 4.2 | |
| Ek/k | 1* | 26.6 | 16.0 | 63.7 | 68.5 | 3.9 | 6.0 |
| 2 | 24.8 | 12.2 | 62.0 | 69.3 | 3.5 | 3.1 | |
Thymocytes from 7- to 8-week-old mice of indicated genotypes were analyzed by flow cytometry. +/+, +/−, and −/− refer to c-cbl genotype.
*
These experiments are shown in Fig. 3A.