Figure 1.

Cluster of HIF target genes in NSC. Unbiased and unsupervised clustering was used to visualize the expressed HIF target genes in a dendrogram. Cluster dendrograms group the patients with the most similar gene expression profiles. The length of the branches represents the dissimilarity. Probe set abundance is displayed on a red-green color scale, with red indicating expression above and green below the mean. This cluster dendrogram uses the HIF target genes to segregate NSC from the healthy controls. Two distinct branches could be identified: one corresponding to the NSC group and the other one to the TN group.